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Biological Medicines
10
Jun
Jun
:Biological Medicines
Biomedical drugs or biological drugs: Medicines taken from biological sources. Vaccines, blood and its products, somatic cells, allergens, biological tissues and recombinant proteins are the most well-known types of biochemicals.
These types of drugs that are distinct from chemical synthesized drugs are based on the protein derived from living cells cultured in the lab. Biomedicals enter the body by injection or intravenous (IV). With the advent of modern and up-to-date molecular biologic techniques, their use in medicine has grown tremendously over the past ten years, although biomedicine has been used to treat the disease for over 100 years.
Biologics are different from traditional systemic drugs that affect the entire immune system, biologists target specific parts of the body’s immune system.
R & D investment in new drugs in the biological industry was $ 65 billion in 2008. Some examples of biologic drugs made with recombinant DNA technology include:
| USAN/INN | Brand | Sickness | Technology | The mechanism of the work |
| Abatacept | Orencia | Rheumatoid Arthritis | Badten CTLA-4 Fusion Protein | Lymphocyte T (T) |
| Adalimumab | Humira & CinnoRA | Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, Psoriasis, Crohns (disease) | Antibody titer | Antagonist (biochemical) agent of alpha-tumor necrosis factor (TNF) |
| alefacept | Amevive | Chronic psoriasis plaque | G1 Protein Fusion Protein | It is not completely clear |
| Erythropoietin | Epogen | Anemia caused by cancer chemotherapy, chronic renal failure, and so on. | Recombinant protein | Stimulates the production of red blood cells |
| Etanercept | Enbrel & Altebrel | Rheumatoid Arthritis, Ankylosing spondylitis, Psoriatic arthritis, Psoriasis | Human recombinant protein receptor-TNF | TNF antagonist |
| Infliximab | Remicade | Rheumatoid Arthritis, Ankylosing spondylitis, Psoriatic arthritis, Psoriasis, Wounded colitis, Crohns (disease) | Monoclonal antibody | TNF antagonist |
| Trastuzumab | Herceptin | Breast Cancer | Human Monoclonal Antibody | Antagonist (HER2 / neu erbB2) |
| Ustekinumab | Stelara | Psoriasis | Human Monoclonal Antibody | Antagonists of IL-12 and IL-23 |
| denileukin diftitox | Ontak | Cellular Lymphoma of the Cell CTCL (T) | Diphtheria poison protein engineer Interleukin 2 and Diphtheria poison | Interleukin receptor adhesive 2 |
| Golimumab | Simponi | Rheumatoid arthritis, psoriatic arthritis, Ankylosing spondylitis, Crohn’s disease (psoriasis), Psoriasis | Antibody titer | TNF antagonist |
